NRF2 Regulates Hyperoxia-induced NOX4 expression in Human Lung Endothelium: Identification of functional antioxidant response elements on NOX4 promoter

Reactive oxygen species (ROS) generated by vascular endothelial and smooth muscle cells contribute to the development and progression of vascular diseases. We have recently shown that hyperoxia enhances NADPH Oxidase 4 (NOX4) expression, which regulates lung endothelial cell migration and angiogenes...

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Detalhes bibliográficos
Main Authors: Pendyala, Srikanth, Moitra, Jaideep, Kalari, Satish, Kleeberger, Steven R., Zhao, Yutong, Reddy, Sekhar P., Garcia, Joe G.N., Natarajan, Viswanathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454485/
https://ncbi.nlm.nih.gov/pubmed/21443946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.03.022
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