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Autophosphorylation-independent and -dependent Functions of Focal Adhesion Kinase during Development

Focal adhesion kinase (FAK) regulates numerous cellular functions and is critical for processes ranging from embryo development to cancer progression. Although autophosphorylation on Tyr-397 appears required for FAK functions in vitro, its role in vivo has not been established. We addressed this que...

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Detalhes bibliográficos
Main Authors: Corsi, Jean-Marc, Houbron, Christophe, Billuart, Pierre, Brunet, Isabelle, Bouvrée, Karine, Eichmann, Anne, Girault, Jean-Antoine, Enslen, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787339/
https://ncbi.nlm.nih.gov/pubmed/19776009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.067280
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