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Advances in Tau-focused drug discovery for Alzheimer's disease and related tauopathies
Neuronal inclusions comprised of the microtubule-associated protein tau are found in a number of neurodegenerative diseases, commonly known as tauopathies. In Alzheimer's disease, the most prevalent tauopathy, misfolded tau is probably a key pathological agent. The recent failure of Aβ-targeted...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787232/ https://ncbi.nlm.nih.gov/pubmed/19794442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2959 |
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