A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

During pre-replication complex (pre-RC) formation, origin recognition complex (ORC), Cdc6, and Cdt1 cooperatively load the 6-subunit mini chromosome maintenance (MCM2-7) complex onto DNA. Loading of MCM2-7 is a prerequisite for DNA licensing that restricts DNA replication to once per cell cycle. Dur...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Evrin, Cecile, Clarke, Pippa, Zech, Juergen, Lurz, Rudi, Sun, Jingchuan, Uhle, Stefan, Li, Huilin, Stillman, Bruce, Speck, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787165/
https://ncbi.nlm.nih.gov/pubmed/19910535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911500106
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados