Protective Efficacy and Immunogenicity of an Adenoviral Vector Vaccine Encoding the Codon-Optimized F Protein of Respiratory Syncytial Virus

Adenoviral vectors (AdV) have received considerable attention for vaccine development because of their high immunogenicity and efficacy. In previous studies, it was shown that DNA immunization of mice with codon-optimized expression plasmids encoding the fusion protein of respiratory syncytial virus...

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Main Authors: Kohlmann, Rebekka, Schwannecke, Sarah, Tippler, Bettina, Ternette, Nicola, Temchura, Vladimir V., Tenbusch, Matthias, Überla, Klaus, Grunwald, Thomas
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786764/
https://ncbi.nlm.nih.gov/pubmed/19776123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01036-09
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