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Protective Efficacy and Immunogenicity of an Adenoviral Vector Vaccine Encoding the Codon-Optimized F Protein of Respiratory Syncytial Virus

Adenoviral vectors (AdV) have received considerable attention for vaccine development because of their high immunogenicity and efficacy. In previous studies, it was shown that DNA immunization of mice with codon-optimized expression plasmids encoding the fusion protein of respiratory syncytial virus...

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Detalhes bibliográficos
Main Authors: Kohlmann, Rebekka, Schwannecke, Sarah, Tippler, Bettina, Ternette, Nicola, Temchura, Vladimir V., Tenbusch, Matthias, Überla, Klaus, Grunwald, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786764/
https://ncbi.nlm.nih.gov/pubmed/19776123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01036-09
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