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Protective Efficacy and Immunogenicity of an Adenoviral Vector Vaccine Encoding the Codon-Optimized F Protein of Respiratory Syncytial Virus

Adenoviral vectors (AdV) have received considerable attention for vaccine development because of their high immunogenicity and efficacy. In previous studies, it was shown that DNA immunization of mice with codon-optimized expression plasmids encoding the fusion protein of respiratory syncytial virus...

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Détails bibliographiques
Auteurs principaux: Kohlmann, Rebekka, Schwannecke, Sarah, Tippler, Bettina, Ternette, Nicola, Temchura, Vladimir V., Tenbusch, Matthias, Überla, Klaus, Grunwald, Thomas
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786764/
https://ncbi.nlm.nih.gov/pubmed/19776123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01036-09
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