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Hepatoma Cell Density Promotes Claudin-1 and Scavenger Receptor BI Expression and Hepatitis C Virus Internalization

Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI). HCV tropism is restricted to the liver, wher...

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Main Authors: Schwarz, Anne K., Grove, Joe, Hu, Ke, Mee, Christopher J., Balfe, Peter, McKeating, Jane A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786758/
https://ncbi.nlm.nih.gov/pubmed/19776133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01552-09
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