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Scavenger Receptor BI and BII Expression Levels Modulate Hepatitis C Virus Infectivity

Hepatitis C virus (HCV) enters cells via a pH- and clathrin-dependent endocytic pathway. Scavenger receptor BI (SR-BI) and CD81 are important entry factors for HCV internalization into target cells. The SR-BI gene gives rise to at least two mRNA splice variants, SR-BI and SR-BII, which differ in the...

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Autores principales: Grove, Joe, Huby, Thierry, Stamataki, Zania, Vanwolleghem, Thomas, Meuleman, Philip, Farquhar, Michelle, Schwarz, Anne, Moreau, Martine, Owen, James S., Leroux-Roels, Geert, Balfe, Peter, McKeating, Jane A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866051/
https://ncbi.nlm.nih.gov/pubmed/17215280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02356-06
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