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Persistence of Transgene Expression Influences CD8(+) T-Cell Expansion and Maintenance following Immunization with Recombinant Adenovirus
Previous studies determined that the CD8(+) T-cell response elicited by recombinant adenovirus exhibited a protracted contraction phase that was associated with long-term presentation of antigen. To gain further insight into this process, a doxycycline-regulated adenovirus was constructed to enable...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786755/ https://ncbi.nlm.nih.gov/pubmed/19759135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00593-09 |
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