Persistence of Transgene Expression Influences CD8(+) T-Cell Expansion and Maintenance following Immunization with Recombinant Adenovirus

Previous studies determined that the CD8(+) T-cell response elicited by recombinant adenovirus exhibited a protracted contraction phase that was associated with long-term presentation of antigen. To gain further insight into this process, a doxycycline-regulated adenovirus was constructed to enable...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Finn, Jonathan D., Bassett, Jennifer, Millar, James B., Grinshtein, Natalie, Yang, Teng Chih, Parsons, Robin, Evelegh, Carole, Wan, Yonghong, Parks, Robin J., Bramson, Jonathan L.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology (ASM) 2009
الموضوعات:
Gene Delivery
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786755/
https://ncbi.nlm.nih.gov/pubmed/19759135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00593-09
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