Mutations in Ribosomal Protein L3 Are Associated with Oxazolidinone Resistance in Staphylococci of Clinical Origin

Following recent reports of ribosomal protein L3 mutations in laboratory-derived linezolid-resistant (LZD(r)) Staphylococcus aureus, we investigated whether similar mutations were present in LZD(r) staphylococci of clinical origin. Sequence analysis of a variety of LZD(r) isolates revealed two L3 mu...

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Bibliographic Details
Main Authors: Locke, Jeffrey B., Hilgers, Mark, Shaw, Karen Joy
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786331/
https://ncbi.nlm.nih.gov/pubmed/19805557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01032-09
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