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Novel Ribosomal Mutations in Staphylococcus aureus Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700)

TR-700 (torezolid), the active moiety of the novel oxazolidinone phosphate prodrug TR-701, is highly potent against gram-positive pathogens, including strains resistant to linezolid (LZD). Here we investigated the potential of Staphylococcus aureus strains ATCC 29213 (methicillin-susceptible S. aure...

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Autori principali: Locke, Jeffrey B., Hilgers, Mark, Shaw, Karen Joy
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786364/
https://ncbi.nlm.nih.gov/pubmed/19752277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00871-09
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