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Specification of Neuronal Polarity Regulated by Local Translation of CRMP2 and Tau via the mTOR-p70S6K Pathway

Mammalian target of rapamycin (mTOR) is an important regulator of neuronal development and functions. Although it was reported recently that mTOR signaling is critical for neuronal polarity, the underlying mechanism remains unclear. Here, we describe the molecular pathway of mTOR-dependent axon spec...

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Auteurs principaux: Morita, Tsuyoshi, Sobue, Kenji
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785701/
https://ncbi.nlm.nih.gov/pubmed/19648118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.008177
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