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Specification of Neuronal Polarity Regulated by Local Translation of CRMP2 and Tau via the mTOR-p70S6K Pathway

Mammalian target of rapamycin (mTOR) is an important regulator of neuronal development and functions. Although it was reported recently that mTOR signaling is critical for neuronal polarity, the underlying mechanism remains unclear. Here, we describe the molecular pathway of mTOR-dependent axon spec...

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Detalhes bibliográficos
Main Authors: Morita, Tsuyoshi, Sobue, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785701/
https://ncbi.nlm.nih.gov/pubmed/19648118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.008177
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