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Rheb and mTOR Regulate Neuronal Polarity through Rap1B
The development of polarized hippocampal neurons with a single axon and multiple dendrites depends on the activity of phosphoinositide 3-kinase (PI3K) and the GTPase Rap1B. Here we show that PI3K regulates axon specification and elongation through the GTPase Rheb and its target mammalian target of r...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662285/ https://ncbi.nlm.nih.gov/pubmed/18842593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802431200 |
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