Inducible Nitric-oxide Synthase Expression Is Regulated by Mitogen-activated Protein Kinase Phosphatase-1

Inducible nitric-oxide (NO) synthase (iNOS) plays a critical role in the eradication of intracellular pathogens. However, the excessive production of NO by iNOS has also been implicated in the pathogenesis of septic shock syndrome. Previously, we have demonstrated that mice deficient in mitogen-acti...

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Detalhes bibliográficos
Main Authors: Wang, Xianxi, Zhao, Qun, Matta, Ranyia, Meng, Xiaomei, Liu, Xiuping, Liu, Chang-Gong, Nelin, Leif D., Liu, Yusen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785641/
https://ncbi.nlm.nih.gov/pubmed/19651781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.051235
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