MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock

Septic shock is a leading cause of morbidity and mortality. However, genetic factors predisposing to septic shock are not fully understood. Excessive production of proinflammatory cytokines, particularly tumor necrosis factor (TNF)-α, and the resultant severe hypotension play a central role in the p...

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Bibliographic Details
Main Authors: Zhao, Qun, Wang, Xianxi, Nelin, Leif D., Yao, Yongxue, Matta, Ranyia, Manson, Mary E., Baliga, Reshma S., Meng, Xiaomei, Smith, Charles V., Bauer, John A., Chang, Cheong-Hee, Liu, Yusen
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118076/
https://ncbi.nlm.nih.gov/pubmed/16380513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051794
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