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MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock
Septic shock is a leading cause of morbidity and mortality. However, genetic factors predisposing to septic shock are not fully understood. Excessive production of proinflammatory cytokines, particularly tumor necrosis factor (TNF)-α, and the resultant severe hypotension play a central role in the p...
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| Hlavní autoři: | , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118076/ https://ncbi.nlm.nih.gov/pubmed/16380513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051794 |
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