HIV-1 Gag Processing Intermediates Trans-dominantly Interfere with HIV-1 Infectivity

Protease inhibitors (PI) act by blocking human immunodeficiency virus (HIV) polyprotein processing, but there is no direct quantitative correlation between the degree of impairment of Gag processing and virion infectivity at low PI concentrations. To analyze the consequences of partial processing, v...

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Detalhes bibliográficos
Main Authors: Müller, Barbara, Anders, Maria, Akiyama, Hisashi, Welsch, Sonja, Glass, Bärbel, Nikovics, Krisztina, Clavel, Francois, Tervo, Hanna-Mari, Keppler, Oliver T., Kräusslich, Hans-Georg
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785601/
https://ncbi.nlm.nih.gov/pubmed/19666477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.027144
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