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Architecture and Regulation of the HIV-1 Assembly and Holding Compartment in Macrophages

Productive infection of macrophages is central to HIV-1 pathogenesis. Newly formed virions bud into a tubular membranous compartment that is contiguous with the plasma membrane. However, little is known about the structure of this compartment and its potential regulation by infection. Here we charac...

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Detalhes bibliográficos
Main Authors: Welsch, Sonja, Groot, Fedde, Kräusslich, Hans-Georg, Keppler, Oliver T., Sattentau, Quentin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147899/
https://ncbi.nlm.nih.gov/pubmed/21613397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00834-11
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