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Cholesterol Regulates Glucose-stimulated Insulin Secretion through Phosphatidylinositol 4,5-Bisphosphate
Membrane cholesterol modulates the ability of glucose to stimulate insulin secretion from pancreatic β-cells. The molecular mechanism by which this occurs is not understood. Here, we show that in cultured β-cells, cholesterol acts through phosphatidylinositol 4,5-bisphosphate (PIP(2)) to regulate ac...
Uloženo v:
| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785582/ https://ncbi.nlm.nih.gov/pubmed/19729450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038034 |
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