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Bestrophin-1 Enables Ca(2+)-activated Cl(−) Conductance in Epithelia

Epithelial cells express calcium-activated Cl(−) channels of unknown molecular identity. These Cl(−) channels play a central role in diseases such as secretory diarrhea, polycystic kidney disease, and cystic fibrosis. The family of bestrophins has been suggested to form calcium-activated Cl(−) chann...

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Main Authors: Barro Soria, René, Spitzner, Melanie, Schreiber, Rainer, Kunzelmann, Karl
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785573/
https://ncbi.nlm.nih.gov/pubmed/17003041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M605716200
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