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Bestrophin-1 Enables Ca(2+)-activated Cl(−) Conductance in Epithelia
Epithelial cells express calcium-activated Cl(−) channels of unknown molecular identity. These Cl(−) channels play a central role in diseases such as secretory diarrhea, polycystic kidney disease, and cystic fibrosis. The family of bestrophins has been suggested to form calcium-activated Cl(−) chann...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785573/ https://ncbi.nlm.nih.gov/pubmed/17003041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M605716200 |
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