Bestrophin 1 Promotes Epithelial-to-mesenchymal Transition of Renal Collecting Duct Cells

Bestrophin 1 (Best1) controls intracellular Ca(2+) concentration, induces Ca(2+)-activated Cl(-) conductance, and increases proliferation of colon carcinoma cells. Here, we show that expression of Best1 in mouse renal collecting duct (CD) cells causes i) an increase in cell proliferation, ii) a loss...

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Detalles Bibliográficos
Main Authors: Aldehni, Fadi, Spitzner, Melanie, Martins, Joana Raquel, Barro-Soria, René, Schreiber, Rainer, Kunzelmann, Karl
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2009
Assuntos:
Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709680/
https://ncbi.nlm.nih.gov/pubmed/19470678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008090987
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