Critical Factors Determining Dimerization of Human Antizyme Inhibitor

Ornithine decarboxylase (ODC) is the first enzyme involved in polyamine biosynthesis, and it catalyzes the decarboxylation of ornithine to putrescine. ODC is a dimeric enzyme, whereas antizyme inhibitor (AZI), a positive regulator of ODC that is homologous to ODC, exists predominantly as a monomer a...

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Hlavní autoři: Su, Kuo-Liang, Liao, Ya-Fan, Hung, Hui-Chih, Liu, Guang-Yaw
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Enzyme Catalysis and Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785365/
https://ncbi.nlm.nih.gov/pubmed/19635796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.007807
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