Activation Induces Structural Changes in the Liganded Angiotensin II Type 1 Receptor

The octapeptide hormone angiotensin II (AngII) binds to and activates the human angiotensin II type 1 receptor (hAT(1)) of the G protein-coupled receptor class A family. Several activation mechanisms have been proposed for this family, but they have not yet been experimentally validated. We previous...

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Bibliographic Details
Main Authors: Clément, Martin, Cabana, Jérôme, Holleran, Brian J., Leduc, Richard, Guillemette, Gaétan, Lavigne, Pierre, Escher, Emanuel
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785348/
https://ncbi.nlm.nih.gov/pubmed/19635801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.012922
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