Bloom DNA Helicase Facilitates Homologous Recombination between Diverged Homologous Sequences

Bloom syndrome caused by inactivation of the Bloom DNA helicase (Blm) is characterized by increases in the level of sister chromatid exchange, homologous recombination (HR) associated with cross-over. It is therefore believed that Blm works as an anti-recombinase. Meanwhile, in Drosophila, DmBlm is...

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Bibliographic Details
Main Authors: Kikuchi, Koji, Abdel-Aziz, H. Ismail, Taniguchi, Yoshihito, Yamazoe, Mitsuyoshi, Takeda, Shunichi, Hirota, Kouji
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785323/
https://ncbi.nlm.nih.gov/pubmed/19661064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.029348
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