Fen-1 Facilitates Homologous Recombination by Removing Divergent Sequences at DNA Break Ends

Homologous recombination (HR) requires nuclease activities at multiple steps, but the contribution of individual nucleases to the processing of double-strand DNA ends at different stages of HR has not been clearly defined. We used chicken DT40 cells to investigate the role of flap endonuclease 1 (Fe...

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Detalhes bibliográficos
Main Authors: Kikuchi, Koji, Taniguchi, Yoshihito, Hatanaka, Atsushi, Sonoda, Eiichiro, Hochegger, Helfrid, Adachi, Noritaka, Matsuzaki, Yasuo, Koyama, Hideki, van Gent, Dik C., Jasin, Maria, Takeda, Shunichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190240/
https://ncbi.nlm.nih.gov/pubmed/16055708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.6948-6955.2005
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