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Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells
Parp-1 and Parp-2 are activated by DNA breaks and have been implicated in the repair of DNA single-strand breaks (SSB). Their involvement in double-strand break (DSB) repair mediated by homologous recombination (HR) or nonhomologous end joining (NHEJ) remains unclear. We addressed this question usin...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1422167/ https://ncbi.nlm.nih.gov/pubmed/16498404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601015 |
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