Brain-derived Neurotrophic Factor Enhances the Basal Rate of Protein Synthesis by Increasing Active Eukaryotic Elongation Factor 2 Levels and Promoting Translation Elongation in Cortical Neurons

The constitutive and activity-dependent components of protein synthesis are both critical for neural function. Although the mechanisms controlling extracellularly induced protein synthesis are becoming clear, less is understood about the molecular networks that regulate the basal translation rate. H...

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Detalhes bibliográficos
Main Authors: Takei, Nobuyuki, Kawamura, Mihoko, Ishizuka, Yuta, Kakiya, Naomasa, Inamura, Naoko, Namba, Hisaaki, Nawa, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785322/
https://ncbi.nlm.nih.gov/pubmed/19625250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.023010
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