Nutlin-3 Affects Expression and Function of Retinoblastoma Protein: ROLE OF RETINOBLASTOMA PROTEIN IN CELLULAR RESPONSE TO NUTLIN-3

The retinoblastoma protein (Rb) plays a pivotal role in regulating cell proliferation and apoptosis. Nutlin-3, a small molecule MDM2 antagonist blocking interaction between MDM2 and p53, activates p53 resulting in cell growth arrest or apoptosis in various cancer cells. However, the molecular basis...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Du, Wei, Wu, Junfeng, Walsh, Erica M., Zhang, Yujun, Chen, Chang Yan, Xiao, Zhi-Xiong Jim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Biomolecular Networks
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785319/
https://ncbi.nlm.nih.gov/pubmed/19648117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046904
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados