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Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus
The regulated expression of large human genes can depend on long-range interactions to establish appropriate three-dimensional structures across the locus. The cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encompasses 189 kb of genomic DNA, shows a complex pattern of express...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785270/ https://ncbi.nlm.nih.gov/pubmed/19897727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900946106 |
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