Catabolism of 4-Hydroxyacids and 4-Hydroxynonenal via 4-Hydroxy-4-phosphoacyl-CoAs

4-Hydroxyacids are products of ubiquitously occurring lipid peroxidation (C(9), C(6)) or drugs of abuse (C(4), C(5)). We investigated the catabolism of these compounds using a combination of metabolomics and mass isotopomer analysis. Livers were perfused with various concentrations of unlabeled and...

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Détails bibliographiques
Auteurs principaux: Zhang, Guo-Fang, Kombu, Rajan S., Kasumov, Takhar, Han, Yong, Sadhukhan, Sushabhan, Zhang, Jianye, Sayre, Lawrence M., Ray, Dale, Gibson, K. Michael, Anderson, Vernon A., Tochtrop, Gregory P., Brunengraber, Henri
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Metabolism and Bioenergetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785196/
https://ncbi.nlm.nih.gov/pubmed/19759021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.055665
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