Metabolomic and Mass Isotopomer Analysis of Liver Gluconeogenesis and Citric Acid Cycle: I. INTERRELATION BETWEEN GLUCONEOGENESIS AND CATAPLEROSIS; FORMATION OF METHOXAMATES FROM AMINOOXYACETATE AND KETOACIDS

We conducted a study coupling metabolomics and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle. Rat livers were perfused with lactate or pyruvate ± aminooxyacetate or mercaptopicolinate in the presence of 40% enriched NaH(13)CO(3). Other livers were perfused with dimethyl [1,...

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Detalhes bibliográficos
Main Authors: Yang, Lili, Kombu, Rajan S., Kasumov, Takhar, Zhu, Shu-Han, Cendrowski, Andrea V., David, France, Anderson, Vernon E., Kelleher, Joanne K., Brunengraber, Henri
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Metabolism and Bioenergetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494924/
https://ncbi.nlm.nih.gov/pubmed/18544527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803454200
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