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A Double Tyrosine Motif in the Cardiac Sodium Channel Domain III-IV Linker Couples Calcium-dependent Calmodulin Binding to Inactivation Gating

Voltage-gated sodium channels maintain the electrical cadence and stability of neurons and muscle cells by selectively controlling the transmembrane passage of their namesake ion. The degree to which these channels contribute to cellular excitability can be managed therapeutically or fine-tuned by e...

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Detalhes bibliográficos
Main Authors: Sarhan, Maen F., Van Petegem, Filip, Ahern, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785169/
https://ncbi.nlm.nih.gov/pubmed/19808664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.052910
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