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Seeing the Forest through the Trees: towards a Unified View on Physiological Calcium Regulation of Voltage-Gated Sodium Channels

Voltage-gated sodium channels (Na(V)s) underlie the upstroke of the action potential in the excitable tissues of nerve and muscle. After opening, Na(V)s rapidly undergo inactivation, a crucial process through which sodium conductance is negatively regulated. Disruption of inactivation by inherited m...

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Detalhes bibliográficos
Main Authors: Van Petegem, Filip, Lobo, Paolo A., Ahern, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514524/
https://ncbi.nlm.nih.gov/pubmed/23283222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.10.020
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