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N-Acylpolyamine Inhibitors of HDM2 and HDMX Binding to p53
Selective inhibition of protein-protein interactions important for cellular processes could lead to the development of new therapies against disease. In the area of cancer, overexpression of the proteins human double minute 2 (HDM2) and its homolog HDMX has been linked to tumor aggressiveness. Both...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784108/ https://ncbi.nlm.nih.gov/pubmed/19880322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.10.032 |
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