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N-Acylpolyamine Inhibitors of HDM2 and HDMX Binding to p53

Selective inhibition of protein-protein interactions important for cellular processes could lead to the development of new therapies against disease. In the area of cancer, overexpression of the proteins human double minute 2 (HDM2) and its homolog HDMX has been linked to tumor aggressiveness. Both...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hayashi, Ryo, Wang, Deyun, Hara, Toshiaki, Iera, Jaclyn A., Durell, Stewart R., Appella, Daniel H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784108/
https://ncbi.nlm.nih.gov/pubmed/19880322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.10.032
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