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Mechamism of VEGF expression by high glucose in proximal tubule epithelial cells

In mouse proximal tubular epithelial cells, high glucose (HG) for 24 h increases VEGF expression at the protein and the mRNA level, suggesting a transcriptional mechanism. HG-induced VEGF synthesis is prevented by captopril, an inhibitor of angiotensin-converting enzyme, and, by losartan, a specific...

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Bibliographic Details
Main Authors: Feliers, Denis, Kasinath, Balakuntalam S.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783935/
https://ncbi.nlm.nih.gov/pubmed/19765632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2009.09.009
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