High glucose induces apoptosis via upregulation of Bim expression in proximal tubule epithelial cells

Diabetic nephropathy is the primary cause of end-stage renal disease. Apoptosis of tubule epithelial cells is a major feature of diabetic nephropathy. The mechanisms of high glucose (HG) induced apoptosis are not fully understood. Here we demonstrated that, HG induced apoptosis via upregulating the...

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Vydáno v:Oncotarget
Hlavní autoři: Zhang, Xiao-Qian, Dong, Jian-Jun, Cai, Tian, Shen, Xue, Zhou, Xiao-Jun, Liao, Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper: Pathology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421832/
https://ncbi.nlm.nih.gov/pubmed/28445931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15491
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