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NDUFS4: Creation of a Mouse Model Mimicking a Complex I Disorder
The Complex I NADH dehydrogenase-ubiquinone-FeS 4 (NDUFS4) subunit gene is involved in proper Complex I function such that the loss of NDUFS4 decreases Complex I activity resulting in mitochondrial disease. Therefore, a mouse model harboring a point mutation in the NDUFS4 gene was created. An embryo...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783808/ https://ncbi.nlm.nih.gov/pubmed/19460290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2009.02.001 |
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