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Crosstalk signaling between mitochondrial Ca(2+) and ROS
Mitochondria are central to energy metabolism as the source of much of the cell’s ATP, as well as being a hub for cellular Ca(2+) signaling. Mitochondrial Ca(2+) is a positive effector of ATP synthesis, yet Ca(2+) overload can lead to mitochondrial dysfunction and cell death. Moreover, Ca(2+) uptake...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683671/ https://ncbi.nlm.nih.gov/pubmed/19273125 |
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