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Crosstalk signaling between mitochondrial Ca(2+) and ROS

Mitochondria are central to energy metabolism as the source of much of the cell’s ATP, as well as being a hub for cellular Ca(2+) signaling. Mitochondrial Ca(2+) is a positive effector of ATP synthesis, yet Ca(2+) overload can lead to mitochondrial dysfunction and cell death. Moreover, Ca(2+) uptake...

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Bibliografiska uppgifter
Huvudupphovsmän: Feissner, Robert F., Skalska, Jolanta, Gaum, Winston E., Sheu, Shey-Shing
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683671/
https://ncbi.nlm.nih.gov/pubmed/19273125
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