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Palladium- and Copper-Catalyzed Solution Phase Synthesis of a Diverse Library of Isoquinolines

The solution phase synthesis of a 111 member isoquinoline library is described. The isoquinoline scaffold has been accessed through the palladium- and copper-catalyzed cyclization of iminoalkynes and the palladium-catalyzed iminoannulation of internal alkynes, followed by diversification of hydroxyl...

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Detalles Bibliográficos
Main Authors: Roy, Sudipta, Roy, Sujata, Neuenswander, Benjamin, Hill, David, Larock, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783704/
https://ncbi.nlm.nih.gov/pubmed/19728736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc9000949
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