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Solution Phase Synthesis of a Diverse Library of Highly Substituted Isoxazoles
The iodocyclization of O-methyloximes of 2-alkyn-1-ones affords 4-iodoisoxazoles, which undergo various palladium-catalyzed reactions to yield 3,4,5-trisubstituted isoxazoles. The palladium-catalyzed processes have been adapted to parallel synthesis utilizing commercially available boronic acid, ace...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750120/ https://ncbi.nlm.nih.gov/pubmed/18671435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc800055x |
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