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Solution-Phase Parallel Synthesis of a Diverse Library of 1,2-Dihydroisoquinolines

Synthesis of a 105 membered library of 1,2-dihydroisoquinolines is described. The 1,2-dihydroisoquinoline compounds have been prepared in good yields using a Lewis acid and organocatalyst-cocatalyzed multicomponent reaction of 2-(1-alkynyl)benzaldehydes, amines and ketones. Various indoles have also...

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Bibliographische Detailangaben
Hauptverfasser: Markina, Nataliya A., Mancuso, Raffaella, Neuenswander, Benjamin, Lushington, Gerald H., Larock, Richard C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118513/
https://ncbi.nlm.nih.gov/pubmed/21410207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co1000794
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