[(3)H]4-(Dimethylamino)-N-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]benzamide, a Selective Radioligand for Dopamine D(3) receptors. II. Quantitative Analysis of Dopamine D(3) and D(2) Receptor Density Ratio in the Caudate-putamen

4-(Dimethylamino)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzamide (WC-10), a N-phenyl piperazine analog, displays high affinity and moderate selectivity for dopamine D(3) receptors versus dopamine D(2) receptors (Chu et al. [2005] Bioorg. Med. Chem. 13; 77–87). In this study, WC-10 was radio...

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Bibliografiske detaljer
Main Authors: Xu, Jinbin, Hassanzadeh, Babak, Chu, Wenhua, Tu, Zhude, Jones, Lynne A., Luedtke, Robert R., Perlmutter, Joel S., Mintun, Mark A., Mach, Robert H.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783604/
https://ncbi.nlm.nih.gov/pubmed/19425052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20652
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