Transcriptomic integration of D(4)R and MOR signaling in the rat caudate putamen

Morphine binding to opioid receptors, mainly to μ opioid receptor (MOR), induces alterations in intracellular pathways essential to the initial development of addiction. The activation of the dopamine D(4) receptor (D(4)R), which is expressed in the caudate putamen (CPu), mainly counteracts morphine...

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Udgivet i:Sci Rep
Main Authors: Valderrama-Carvajal, Alejandra, Irizar, Haritz, Gago, Belén, Jiménez-Urbieta, Haritz, Fuxe, Kjell, Rodríguez-Oroz, María C., Otaegui, David, Rivera, Alicia
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943359/
https://ncbi.nlm.nih.gov/pubmed/29743514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25604-4
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