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The Adenylyl Cyclase Activity of Anthrax Edema Factor
Bacillus anthracis, the etiologic agent for anthrax, secretes edema factor (EF) to disrupt intracellular signaling pathways. Upon translocation into host cells and association with a calcium sensor, calmodulin (CaM), EF becomes a highly active adenylyl cyclase (AC) that raises the intracellular conc...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783455/ https://ncbi.nlm.nih.gov/pubmed/19560485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2009.06.001 |
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