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The Adenylyl Cyclase Activity of Anthrax Edema Factor
Bacillus anthracis, the etiologic agent for anthrax, secretes edema factor (EF) to disrupt intracellular signaling pathways. Upon translocation into host cells and association with a calcium sensor, calmodulin (CaM), EF becomes a highly active adenylyl cyclase (AC) that raises the intracellular conc...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783455/ https://ncbi.nlm.nih.gov/pubmed/19560485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2009.06.001 |
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