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MUC1 ONCOPROTEIN IS A DRUGGABLE TARGET IN HUMAN PROSTATE CANCER CELLS

Human prostate cancers are dependent on the androgen receptor for their progression. The MUC1 heterodimeric oncoprotein is aberrantly overexpressed in prostate cancers; however, it is not known if MUC1 is of functional importance to these tumors. To assess dependence on MUC1, we synthesized an inhib...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Joshi, Maya Datt, Ahmad, Rehan, Yin, Li, Raina, Deepak, Rajabi, Hasan, Bubley, Glenn, Kharbanda, Surender, Kufe, Donald
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783220/
https://ncbi.nlm.nih.gov/pubmed/19887552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0646
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