Unique Ligand Binding Patterns Between Estrogen Receptor α and β Revealed by Hydrogen/Deuterium Exchange

Here we present the use of hydrogen/deuterium exchange (HDX) mass spectrometry to analyze the estrogen receptor β ligand binding domain (ERβLBD) in the absence and presence of a variety of chemical compounds with different binding modes and pharmacological properties. Previously, we reported the use...

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Bibliographische Detailangaben
Hauptverfasser: Dai, Susie Y., Burris, Thomas P., Dodge, Jeffrey A., Montrose-Rafizadeh, Chahrzad, Wang, Yong, Pascal, Bruce D., Chalmers, Michael J., Griffin, Patrick R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782520/
https://ncbi.nlm.nih.gov/pubmed/19739677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901149t
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